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Researchers from two New York City HIV treatment centres reviewed all published data regarding methamphetamine use and the relationship to HIV infection and treatment failure. The study was conducted as a systematic review and included only articles in English language journals. The investigators found that meth users were more likely to have a history of injecting heroin, comorbid mental illness, and been diagnosed with HIV infection at a younger age than either MSM or HCP who had not used methamphetamine. One of the primary reasons for this difference in demographics is the use of methamphetamine by younger, homosexual men and then moving up the age scale.

"It's quite possible that methamphetamine use is becoming a significant issue in the management of HIV infection," the investigators write. "While clinical research indicates that there is a risk of harm from drug use, especially injection drug use, the potential for benefit from methamphetamine use remains unclear, and should not necessarily be viewed as a contraindication to therapy."

The vast majority of methamphetamine users in the US and elsewhere use either snorting or smoking the drug. Methamphetamine can be snorted readily in powder form and also can be smoked in cigarette form which is very commonly used in the US and western Europe. Most actual users are smokers, but "squatters" and those who do not feel like smoking may snort instead of smoking. The snorting method of use poses a potential problem because it is harder to control the amount of methamphetamine that is taken. Methamphetamine is a diuretic and will increase the risk of severe dehydration if someone is not careful. Ingestion of methamphetamine leads to rapid and intense elevation of mood, which is known as "getting high. " Not surprisingly, methamphetamine users are attracted to dance clubs and the "rave" scene, as these places provide a high-energy environment where mutual "getting high" can be more easily achieved. d2c66b5586